Effectiveness of Methanol Extract of Moringa oleifera Lam. Leaf as Antibacterial Drug to Bacterial Triggers of Urinary Tract Infections In vitro

Background: Urinary tract infections (UTIs) are a severe public health problem and caused by range of pathogens, but most commonly Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis Staphylococcus saprophyticus. High recurrence rates increasing antimicrobial resistance among uropathogens threaten to greatly increase the economic burden these infections. This study aimed measure lowest concentration Moringa oleifera Lam. Leaf that did not show any growth tested microorganisms.
 Methods: The antibacterial activity test was adapted from CLSI broth microdilution assay, with minor modifications, were used for evaluation M. extracts against bacteria. Three concentrations higher than MIC standard cultured on MHA. agar which found bacterial colonies determined as MBC.
 Results: results showed leaf extract could inhibit growth. Inhibition based concentration. For E. coli bacteria, highest absorbance value at 100mg/ml (2.86±0.02); even when diluted 3,13 mg/ml (1.08±0.01), moringa growth, although differ negative control (0.13±0.06). same others bacteria UTIs.
 Conclusions: Methanol can bactericide urinary